GRADED NODAL RESPONSE IN NaCl-DEFICIENT MEDIA, AND THE CRITICAL NaCl-CONCENTRATION FOR “EXCITATION”
نویسندگان
چکیده
منابع مشابه
Conduction of nervous impulses in NaCl-deficient media.
Since Overton's finding on muscle (1), examination on the effect of Na deficient media upon the nervous function has been a centre of interest (27). The blocking concentration, or the minimal concentration required for conduction, has been said to be 10-15% of that of the normal Ringer for nonmyelinated fibres of the Crustacean (4) and 0.011 M for myelinated fibres of the frog (5), which are al...
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متن کاملRenal expression of parvalbumin is critical for NaCl handling and response to diuretics.
The distal convoluted tubule (DCT) plays an essential role in the reabsorption of NaCl by the kidney, a process that can be inhibited by thiazide diuretics. Parvalbumin (PV), a Ca(2+)-binding protein that plays a role in muscle fibers and neurons, is selectively expressed in the DCT, where its role remains unknown. We therefore investigated the renal phenotype of PV knockout mice (Pvalb(-/-)) v...
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ژورنال
عنوان ژورنال: The Japanese Journal of Physiology
سال: 1959
ISSN: 1881-1396,0021-521X
DOI: 10.2170/jjphysiol.9.304